Summers are becoming less tolerable for everyone lately. Yet, it may be worse for people living with neurological conditions. Certain medications can make it harder for your body to cope with high temperatures. This can increase your risk for heat-related illnesses.
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Why heat can be a bigger risk with certain medications

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Some medications prescribed for neurological conditions can interfere with your body’s ability to sweat, regulate temperature, or stay hydrated. Others may cause drowsiness or dizziness, which can make it difficult to recognize early signs of heat stress.
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‍When your nervous system and your medications are both involved in temperature regulation. This reduces your body’s ability to adapt to heat.
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Medications that may increase heat-related risks
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If you take any of these, it’s worth being extra cautious in hot weather:
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• Tricyclic antidepressants
• Atypical antidepressants
• SSRIs and SNRIs
• Seizure medications
• Benzodiazepines
• Gabapentinoids (gabapentin, pregabalin)
• Beta blockers
• Calcium channel blockers
• Diuretics
• Antihistamines
• Anticholinergics
• Stimulants
• Triptans
• Ergotamines
• Pyridostigmine

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Note: This is not a complete list. Always check with your prescribing provider or pharmacist about your specific medications.
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Signs of heat intolerance to watch for
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• Excessive sweating or inability to sweat
• Fatigue or weakness
• Dizziness or lightheadedness
• Headache
• Nausea or vomiting
• Confusion or disorientation
• Muscle cramps
• Increased heart rate or breathing rate
• Hot flashes or flushed skin

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If you notice these signs, get to a cooler place immediately. Hydrate, and seek medical attention if symptoms do not improve.
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How to protect yourself in the heat
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• Stay ahead on hydration. Drink at least 1.5 times your body weight (in kilograms) in ounces of water per day (unless otherwise advised by your provider).
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• Add electrolytes. Especially if you’re sweating a lot or on diuretics. ‍
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• Avoid peak heat hours. Try to schedule outdoor activities before 11 AM or after 3 PM. ‍
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• Wear lightweight, breathable clothing. ‍
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• Keep cooling tools handy. Cooling towels, spray bottle fans, or portable ice packs can make a big difference. ‍
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• Know your weather risks. Track the heat index and air quality index, especially during wildfire season or in high-humidity climates.
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• Check in with your provider. If you notice your heat tolerance is worsening or your symptoms flare significantly in the heat, ask about medication timing or dose adjustments.

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Neura patients can always reach out to their provider through the in-app chat or email support@neurahealth.co to discuss concerns about how their medication may affect their heat tolerance.

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