Neura members can now hold video appointments with Dr. Indranil Sen-Gupta, MD. If you'd like to book an appointment, start your Neura trial membership today!

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Meet Dr. Indranil Sen-Gupta: Neura Health’s Expert in Epilepsy and Clinical Neurophysiology

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At Neura Health, we’re committed to providing comprehensive, expert neurological care—and we’re excited to introduce Dr. Indranil Sen-Gupta, MD, a board-certified neurologist specializing in epilepsy, refractory seizure management, and clinical neurophysiology. Whether you're living with difficult-to-treat seizures, looking to minimize medication side effects, or exploring advanced treatment options like neurostimulation, Dr. Sen-Gupta is here to help.

A Deep Understanding of Seizure Disorders‍

Dr. Sen-Gupta’s unique path to medicine began with a passion for computers and systems engineering in his hometown of Silicon Valley. After earning an undergraduate degree in electrical engineering, he was drawn to the parallels between computer troubleshooting and diagnosing the brain’s electrical activity—eventually leading him into the field of neurology.

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He completed fellowship training in epilepsy and clinical neurophysiology at UCLA and spent close to a decade as an Associate Clinical Professor at UC Irvine Medical Center, where he directed fellowship programs and provided specialized care in EEG, intraoperative monitoring, and epilepsy.

Expert Care for Complex Epilepsy Cases

At Neura Health, Dr. Sen-Gupta focuses on the management of:

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• Refractory epilepsy (seizures that persist despite medication)
  
  
• Epilepsy diagnostics using EEG and neuroimaging
  
  
• Advanced treatment strategies, including neurostimulation and surgical referrals
  
  
• Medication optimization to reduce side effects
  
  
• Patient education and seizure prevention planning
  
  

His approach emphasizes early identification of treatment-resistant epilepsy and exploring the full range of interventions available. “When seizures don’t respond to medications, it’s a signal to look deeper—not just add another prescription,” he explains.

A Collaborative Approach to Neurological Health‍

Dr. Sen-Gupta believes that successful epilepsy management isn’t just about medications—it’s about teamwork. He works closely with patients, caregivers, and Neura Health coaches to build a care plan that supports long-term health, safety, and quality of life.

From understanding seizure triggers and side effect management to evaluating candidacy for newer therapies, he’s committed to making sure every patient feels supported, informed, and empowered.

Connecting Patients to Community and Resources

In addition to clinical care, Dr. Sen-Gupta is a strong advocate for epilepsy education and community support. He frequently refers patients to national and local organizations like the Epilepsy Foundation, Epilepsy Support Network of Orange County, and other grassroots groups that provide education, peer connection, and updates on the latest advancements in epilepsy research and care.

Get Started with Dr. Sen-Gupta at Neura Health‍

Ready to take the next step in your epilepsy care? Dr. Sen-Gupta is now seeing patients virtually through Neura Health—bringing expert, personalized neurology care right to your home.

Book a visit today and discover how he can help you better understand your condition, explore new treatment options, and work toward complete seizure control.

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Video Transcript: 

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 Hi, I'm Neil Sen-Gupta. I am an epileptologist by training, so I specialize in the treatment of patients with seizure disorders and also have clinical neurophysiology training, so I do a lot of intraoperative monitoring as well.

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What first brought you to medicine?

I grew up in the Silicon Valley in the Bay Area, and as a kid, I always had a strong interest in computers, I ended up specializing in electrical engineering for my undergraduate and really enjoyed working with computers. During that time, I also realized that I wanted to apply this towards the treatment of people so I went into medical school after that and through that, I ended up finding neurology, which seemed to have many principles in common with how computers are diagnosed and troubleshot and that sort of thing. Being able to apply those to people and their treatment really was a good connection within the field of neurology.

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Within neurology itself, seizure disorders involve a lot of these principles of being able to localize and understand where seizures are coming from, and how things are manifesting, and a lot of the initial interest that I had in the technical aspect is really present in a lot of the diagnosis of epilepsy, like through EEG, and they're figuring out where seizures are coming from based off of other techniques.

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I ended up pursuing a fellowship training at UCLA for epilepsy and clinical neurophysiology. Then I was on staff at UC Irvine for multiple years before transitioning over to my current position doing intraoperative monitoring and with Neura Health for epilepsy management.

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What’s your special interest within your specific field?‍

My interest is in patients who have ongoing seizures, what we call refractory seizures, where patients continue to have seizures despite trials of two seizure medications, whether together or in conjunction, and that's where we start thinking about other potential avenues beyond just medications. Such as perhaps neurostimulation devices or evaluations to see if there's a particular area in the brain that could be localized to try to remove, for instance, or add a stimulator to see if the seizure control can improve.

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So my interest in epilepsy is in refractory seizures that stay difficult to treat despite seizure medications alone.

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What’s your approach to treating patients?‍

I think the first, especially for the field of epilepsy, is an understanding of why seizures are happening and if there's a particular cause that we can find for these seizures, and more importantly, it's rapid access to care. It's known that for epilepsy, specifically, there's often a long delay between the onset of people having difficult-to-control seizures and then being routed to the right places to be able to get definitive management if they're not going to be controlled with medications alone.

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So being able to really understand and identify when someone is having these refractory seizures that require a higher expertise as far as a center that offers things like invasive monitoring or in-house monitoring for seizures to be able to understand where they're coming from and is there potentially a role for stimulation or surgery is really important.

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It's known there's a long delay usually for that happening and our goal certainly is to make that process a lot faster. The other part, of course, is just for the majority of patients whose seizures are well controlled on seizure medications, just making sure that they again have an understanding of the fact of why they need to take seizure medications regularly, how to avoid triggers that could precipitate their seizures and also to make sure they're not having side effects to their medications.

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A lot of times I think patients end up just tolerating side effects because they're just so used to being on a medicine for so long. They accept it as normal. Fortunately, in the field of epilepsy in the last 10 to 15 years, there's been so many new medications that have come out that it's certainly possible to try to find something that's more user-friendly.

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And every person is different as far as how they respond to different medications. Trying for the patients with seizures that are well controlled, making sure that they're also not having intolerable side effects, and optimizing them from that standpoint as much as possible.

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What is your POV on patient-first care?

For epilepsy in particular, a team-based approach is really what comes to mind in that regard. Not that the patient should be the passive recipient of care of, hey, take this medicine and here, let's add that, and okay, you're having some seizures, no big deal. We'll add some more medications and that'll be it.

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Maybe we'll have a seizure every now and then. No, it's really about understanding that the goal is to get to full seizure control and that if we're not there, what else can we do to try to optimize? But certainly there are some instances where we might not be able to achieve that, but to get as close as possible to that goal and make sure that we've exhausted all the appropriate avenues to get there is really important. The other part of that is the appropriate counseling. So again, part of a team with the health coach to see about how we correctly take seizure medications? How can we schedule things to make sure that there aren't inadvertently missed dosages? What kind of triggers might there be that we can potentially avoid or minimize like alcohol or sleep deprivation and that sort of thing. So really to have the counseling of the resources where patients have that sort of autonomy to realize that they're just not being told what to do and having to accept they're a team, a support team that's there to be vested in their care and guide them through the process of epilepsy management.

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What advocacy groups do you feel passionately about?

Certainly, there are organizations for epilepsy support like the Epilepsy Support Network of Orange County, and Epilepsy Alliance that are available as resources. There are groups like the Epilepsy Foundation, which is a nationwide group. And then within that, there are many more statewide and local affiliates for support.

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And then there are many grassroots organizations as well for epilepsy care, depending on where someone might live and it's certainly helpful to get plugged into those resources and those networks. One key reason is that the realization is that there are multiple. Patients who are undergoing similar shared experiences with this. Epilepsy is one of these things where one in a hundred people across the planet is dealing with epilepsy, and yet we don't hear about this anywhere to the extent as we do of other rarer conditions that sort of get the media forefront. And for this reason, it's important to have access to these advocacy groups. Epilepsy Foundation is one that's nationwide and again, there's multiple other small organizations that might be more local that also exist.

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So getting those resources, depending on where someone lives, often have events that occur sometimes monthly, every couple of months, where there can be a chance to talk to physicians who provide care for patients with epilepsy to understand what the latest developments are or to learn more about certain subtopics like epilepsy and sleep, or epilepsy and mood, women's issues and epilepsy.

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These are all really helpful to learn about and also more importantly, get to meet other patients and families who are also enduring similar kinds of experiences.

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